Excretion Patterns of Urinary Metabolites of Estradiol-4-C'4 in Postmenopausal Women with Benign and Malignant Disease of the Breast1
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چکیده
activity of estrogenic hormones (either of endogenous or exogenous origin) and the growth of mammary carcinoma in humans. Ablation of the hypophysis, the endocrine glands producing estrogens, or the administration of estrogenic hormones may induce objective regression of tumor in approximately 30 % of the patients so treated (18, 19). The basic nature of this relationship between carcinoma of the breast and the metabolism of estrogens in humans is obscure. As part of a broad study of this phenomenon, estrogen metabolism, as reflected by the urinary excretion of isotopically labeled estradiol, was investigated in a group of postmenopausal women with
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Twenty-four-hour preoperative endocrine profiles in women with benign and malignant breast disease.
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